Association between first-line antidepressant use and risk of dementia in older adults: a retrospective cohort study
This study by Wang et al. (2023) concludes that adults aged 50 and above with depression (2,710 patients) receiving SSRIs/SNRIs (89% of patients) were associated with an increased dementia risk (16% vs 13%) compared to those receiving psychotherapy (11% of patients).
So, 27% more likely to get dementia.
The paper doesn’t address the reasons some patients were given meds and others were given psychotherapy.
This does not prove that the meds were causing dementia.
Link: https://doi.org/10.21203/rs.3.rs-3266805/v1
APA Reference: Wang, H.-M. G., Chen, W.-H., Chang, S.-H., Zhang, T., Shao, H., Guo, J., & Wei-Hsuan Lo-Ciganic. (2023). Association between first-line antidepressant use and risk of dementia in older adults: a retrospective cohort study. Research Square (Research Square). https://doi.org/10.21203/rs.3.rs-3266805/v1